The role of Ca2+ influx in endocytic vacuole formation in pancreatic acinar cells

The inducers of acute pancreatitis trigger a prolonged increase in the cytosolic Ca2+ concentration ([Ca2+]c), which is responsible for the damage to and eventual death of pancreatic acinar cells. Vacuolization is an important indicator of pancreatic acinar cell damage. Furthermore, activation of tr...

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Bibliographic Details
Main Authors: Voronina, Svetlana, Collier, David, Chvanov, Michael, Middlehurst, Ben, Beckett, Alison J., Prior, Ian A., Criddle, David N., Begg, Malcolm, Mikoshiba, Katsuhiko, Sutton, Robert, Tepikin, Alexei V.
Format: Online
Language:English
Published: Portland Press Ltd. 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4303308/