Experimentally-Derived Fibroblast Gene Signatures Identify Molecular Pathways Associated with Distinct Subsets of Systemic Sclerosis Patients in Three Independent Cohorts

Experimentally-Derived Fibroblast Gene Signatures Identify Molecular Pathways Associated with Distinct Subsets of Systemic Sclerosis Patients in Three Independent Cohorts

Genome-wide expression profiling in systemic sclerosis (SSc) has identified four ‘intrinsic’ subsets of disease (fibroproliferative, inflammatory, limited, and normal-like), each of which shows deregulation of distinct signaling pathways; however, the full set of pathways contributing to this differ...

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Bibliographic Details
Main Authors: Johnson, Michael E., Mahoney, J. Matthew, Taroni, Jaclyn, Sargent, Jennifer L., Marmarelis, Eleni, Wu, Ming-Ru, Varga, John, Hinchcliff, Monique E., Whitfield, Michael L.
Format: Online
Language:English
Published: Public Library of Science 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4301872/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4301872/

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