Protective Role for Caspase-11 during Acute Experimental Murine Colitis

Protective Role for Caspase-11 during Acute Experimental Murine Colitis

Activation of the noncanonical inflammasome, mediated by caspase-11, serves as an additional pathway for the production of the proinflammatory cytokines IL-1β and IL-18. Noncanonical inflammasome activity occurs during host defense against Gram-negative bacteria and in models of acute septic shock....

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Bibliographic Details
Main Authors: Oficjalska, Katarzyna, Raverdeau, Mathilde, Aviello, Gabriella, Wade, Siobhan C., Hickey, Ana, Sheehan, Katherine M., Corr, Sinead C., Kay, Elaine W., O’Neill, Luke A., Mills, Kingston H. G., Creagh, Emma M.
Format: Online
Language:English
Published: AAI 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4298125/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4298125/

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