The mitochondrial permeability transition pore: Molecular nature and role as a target in cardioprotection
The mitochondrial permeability transition (PT) – an abrupt increase permeability of the inner membrane to solutes – is a causative event in ischemia–reperfusion injury of the heart, and the focus of intense research in cardioprotection. The PT is due to opening of the PT pore (PTP), a high conductan...
Main Authors: | , |
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Format: | Online |
Language: | English |
Published: |
Academic Press
2015
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4294587/ |