The Mitochondrial Permeability Transition Pore and Cancer: Molecular Mechanisms Involved in Cell Death

Since its discovery in the 1970s, the mitochondrial permeability transition (MPT) has been proposed to be a strategic regulator of cell death. Intense research efforts have focused on elucidating the molecular components of the MPT because this knowledge may help to better understand and treat vario...

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Bibliographic Details
Main Authors: Bonora, Massimo, Pinton, Paolo
Format: Online
Language:English
Published: Frontiers Media S.A. 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4235083/