The pancreatic cancer microenvironment: an immunologic battleground

Recent studies of human pancreatic cancer challenge the mouse model-derived notion that the pancreas is a site of immune privilege. A heavy infiltration of CD8+ T cells expressing programmed cell death 1 (PD-1) and smaller numbers of myeloid cells and regulatory T cells provides rationale for the cl...

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Bibliographic Details
Main Author: Pillarisetty, Venu G
Format: Online
Language:English
Published: Taylor & Francis 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4292569/