Using continuous data on tumour measurements to improve inference in phase II cancer studies

In phase II cancer trials, tumour response is either the primary or an important secondary endpoint. Tumour response is a binary composite endpoint determined, according to the Response Evaluation Criteria in Solid Tumors, by (1) whether the percentage change in tumour size is greater than a prescri...

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Bibliographic Details
Main Authors: Wason, James MS, Seaman, Shaun R
Format: Online
Language:English
Published: BlackWell Publishing Ltd 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4282550/