Bovine FcRn-Mediated Human Immunoglobulin G Transfer across the Milk-Blood Barrier in Transgenic Mice

Maternal-fetal IgGs transport occurs either prenatally or postnatally, which confers the newborns with passive immunity before their own immune system has matured. However, little is known about the mechanisms of postnatal IgGs passage in the mammary gland. To investigate how FcRn mediates the IgGs...

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Bibliographic Details
Main Authors: Cui, Dan, Zhang, Linlin, Li, Jia, Zhao, Yaofeng, Hu, Xiaoxiang, Dai, Yunping, Zhang, Ran, Li, Ning
Format: Online
Language:English
Published: Public Library of Science 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4278800/