Mu Opioid Receptor Binding Correlates with Nicotine Dependence and Reward in Smokers

Mu Opioid Receptor Binding Correlates with Nicotine Dependence and Reward in Smokers

The rewarding effects of nicotine are associated with activation of nicotine receptors. However, there is increasing evidence that the endogenous opioid system is involved in nicotine's rewarding effects. We employed PET imaging with [11C]carfentanil to test the hypotheses that acute cigarette...

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Bibliographic Details
Main Authors: Kuwabara, Hiroto, Heishman, Stephen J., Brasic, James R., Contoreggi, Carlo, Cascella, Nicola, Mackowick, Kristen M., Taylor, Richard, Rousset, Olivier, Willis, William, Huestis, Marilyn A., Concheiro, Marta, Wand, Gary, Wong, Dean F., Volkow, Nora D.
Format: Online
Language:English
Published: Public Library of Science 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4262264/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4262264/

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