Targeted Expression of Mu-Opioid Receptors in a Subset of Striatal Direct-Pathway Neurons Restores Opiate Reward

Targeted Expression of Mu-Opioid Receptors in a Subset of Striatal Direct-Pathway Neurons Restores Opiate Reward

Mu-Opioid Receptors (MOR) are necessary for the analgesic and addictive effects of opioids such as morphine, but the MOR-expressing neuronal populations that mediate the distinct opiate effects remain elusive. Here we devised a novel conditional BAC rescue strategy to show that mice with targeted MO...

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Bibliographic Details
Main Authors: Cui, Yijun, Ostlund, Sean B., James, Alex, Park, Chang Sin, Ge, Weihong, Roberts, Kristofer W., Mittal, Nitish, Murphy, Niall P., Cepeda, Carlos, Kieffer, Brigitte L., Levine, Michael S., Jentsch, J. David, Walwyn, Wendy M., Sun, Yi E., Evans, Christopher J., Maidment, Nigel T., Yang, X. William
Format: Online
Language:English
Published: 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4008330/

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4008330/

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