MHC-Ig induces memory T cell formation in vivo and inhibits tumour growth

Induction of a T cell mediated immune response is critical for the eradication of viral infections and tumours. Soluble peptide-loaded major histocompatibility complex-Ig (pep−MHC-Ig) have been shown to bind their cognate ligands, T cell receptor, with high affinity, and are successfully used to vis...

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Bibliographic Details
Main Authors: Schütz, Christian, Zoso, Alessia, Peng, Shiwen, Bennett, Jonathon D, Schneck, Jonathan P, Oelke, Mathias
Format: Online
Language:English
Published: BlackWell Publishing Ltd 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4257763/