Murine Anti-vaccinia Virus D8 Antibodies Target Different Epitopes and Differ in Their Ability to Block D8 Binding to CS-E

Murine Anti-vaccinia Virus D8 Antibodies Target Different Epitopes and Differ in Their Ability to Block D8 Binding to CS-E

The IMV envelope protein D8 is an adhesion molecule and a major immunodominant antigen of vaccinia virus (VACV). Here we identified the optimal D8 ligand to be chondroitin sulfate E (CS-E). CS-E is characterized by a disaccharide moiety with two sulfated hydroxyl groups at positions 4′ and 6′ of Gal...

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Bibliographic Details
Main Authors: Matho, Michael H., de Val, Natalia, Miller, Gregory M., Brown, Joshua, Schlossman, Andrew, Meng, Xiangzhi, Crotty, Shane, Peters, Bjoern, Xiang, Yan, Hsieh-Wilson, Linda C., Ward, Andrew B., Zajonc, Dirk M.
Format: Online
Language:English
Published: Public Library of Science 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4256255/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4256255/

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