Well-Ordered Trimeric HIV-1 Subtype B and C Soluble Spike Mimetics Generated by Negative Selection Display Native-like Properties

by Guenaga, Javier, de Val, Natalia, Tran, Karen, Feng, Yu, Satchwell, Karen, Ward, Andrew B., Wyatt, Richard T.
Published 2015

Thermostability of Well-Ordered HIV Spikes Correlates with the Elicitation of Autologous Tier 2 Neutralizing Antibodies

by Feng, Yu, Tran, Karen, Bale, Shridhar, Kumar, Shailendra, Guenaga, Javier, Wilson, Richard, de Val, Natalia, Arendt, Heather, DeStefano, Joanne, Ward, Andrew B., Wyatt, Richard T.
Published 2016

Structures of Ebola Virus GP and sGP in Complex with Therapeutic Antibodies

by Pallesen, Jesper, Murin, Charles D., de Val, Natalia, Cottrell, Christopher A., Hastie, Kathryn M., Turner, Hannah L., Fusco, Marnie L., Flyak, Andrew I., Zeitlin, Larry, Crowe, James E., Andersen, Kristian G., Saphire, Erica Ollmann, Ward, Andrew B.
Published 2016

Chemical Cross-Linking Stabilizes Native-Like HIV-1 Envelope Glycoprotein Trimer Antigens

by Schiffner, Torben, de Val, Natalia, Russell, Rebecca A., de Taeye, Steven W., de la Peña, Alba Torrents, Ozorowski, Gabriel, Kim, Helen J., Nieusma, Travis, Brod, Florian, Cupo, Albert, Sanders, Rogier W., Moore, John P., Ward, Andrew B., Sattentau, Quentin J.
Published 2015

Murine Anti-vaccinia Virus D8 Antibodies Target Different Epitopes and Differ in Their Ability to Block D8 Binding to CS-E

by Matho, Michael H., de Val, Natalia, Miller, Gregory M., Brown, Joshua, Schlossman, Andrew, Meng, Xiangzhi, Crotty, Shane, Peters, Bjoern, Xiang, Yan, Hsieh-Wilson, Linda C., Ward, Andrew B., Zajonc, Dirk M.
Published 2014

Presenting native-like trimeric HIV-1 antigens with self-assembling nanoparticles

by He, Linling, de Val, Natalia, Morris, Charles D., Vora, Nemil, Thinnes, Therese C., Kong, Leopold, Azadnia, Parisa, Sok, Devin, Zhou, Bin, Burton, Dennis R., Wilson, Ian A, Nemazee, David, Ward, Andrew B., Zhu, Jiang
Published 2016

Uncleaved prefusion-optimized gp140 trimers derived from analysis of HIV-1 envelope metastability

by Kong, Leopold, He, Linling, de Val, Natalia, Vora, Nemil, Morris, Charles D., Azadnia, Parisa, Sok, Devin, Zhou, Bin, Burton, Dennis R., Ward, Andrew B., Wilson, Ian A., Zhu, Jiang
Published 2016

A Next-Generation Cleaved, Soluble HIV-1 Env Trimer, BG505 SOSIP.664 gp140, Expresses Multiple Epitopes for Broadly Neutralizing but Not Non-Neutralizing Antibodies

by Sanders, Rogier W., Derking, Ronald, Cupo, Albert, Julien, Jean-Philippe, Yasmeen, Anila, de Val, Natalia, Kim, Helen J., Blattner, Claudia, de la Peña, Alba Torrents, Korzun, Jacob, Golabek, Michael, de los Reyes, Kevin, Ketas, Thomas J., van Gils, Marit J., King, C. Richter, Wilson, Ian A., Ward, Andrew B., Klasse, P. J., Moore, John P.
Published 2013

Tailored Immunogens Direct Affinity Maturation toward HIV Neutralizing Antibodies

by Briney, Bryan, Sok, Devin, Jardine, Joseph G., Kulp, Daniel W., Skog, Patrick, Menis, Sergey, Jacak, Ronald, Kalyuzhniy, Oleksandr, de Val, Natalia, Sesterhenn, Fabian, Le, Khoa M., Ramos, Alejandra, Jones, Meaghan, Saye-Francisco, Karen L., Blane, Tanya R., Spencer, Skye, Georgeson, Erik, Hu, Xiaozhen, Ozorowski, Gabriel, Adachi, Yumiko, Kubitz, Michael, Sarkar, Anita, Wilson, Ian A., Ward, Andrew B., Nemazee, David, Burton, Dennis R., Schief, William R.
Published 2016