Interferon-Inducible Cholesterol-25-Hydroxylase Inhibits Hepatitis C Virus Replication via Distinct Mechanisms

Interferon-Inducible Cholesterol-25-Hydroxylase Inhibits Hepatitis C Virus Replication via Distinct Mechanisms

Cholesterol 25-hydroxylase (CH25H) as an interferon-stimulated gene (ISG) has recently been shown to exert broad antiviral activity through the production of 25-hydroxycholesterol (25HC), which is believed to inhibit the virus-cell membrane fusion during viral entry. However, little is known about t...

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Bibliographic Details
Main Authors: Chen, Yongzhi, Wang, Shanshan, Yi, Zhaohong, Tian, Huabin, Aliyari, Roghiyh, Li, Yanhua, Chen, Gang, Liu, Ping, Zhong, Jin, Chen, Xinwen, Du, Peishuang, Su, Lishan, Qin, F. Xiao-Feng, Deng, Hongyu, Cheng, Genhong
Format: Online
Language:English
Published: Nature Publishing Group 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4252895/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4252895/

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