Evaluation of Infective Property of Recombinant Prion Protein Amyloids in Cultured Cells Overexpressing Cellular Prion Protein

Misfolded isoform of prion protein (PrP), termed scrapie PrP (PrPSc), tends to aggregate into various fibril forms. Previously, we reported various conditions that affect aggregation of recombinant PrP into amyloids. Because amyloidogenesis of PrP is closely associated with transmissible spongiform...

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Bibliographic Details
Main Authors: Kim, Dae-Hwan, Lee, Hye-Mi, Ryou, Chongsuk
Format: Online
Language:English
Published: The Korean Academy of Medical Sciences 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4248579/