In Vitro Amplification of Misfolded Prion Protein Using Lysate of Cultured Cells

In Vitro Amplification of Misfolded Prion Protein Using Lysate of Cultured Cells

Protein misfolding cyclic amplification (PMCA) recapitulates the prion protein (PrP) conversion process under cell-free conditions. PMCA was initially established with brain material and then with further simplified constituents such as partially purified and recombinant PrP. However, availability o...

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Bibliographic Details
Main Authors: Mays, Charles E., Yeom, Jihyun, Kang, Hae-Eun, Bian, Jifeng, Khaychuk, Vadim, Kim, Younghwan, Bartz, Jason C., Telling, Glenn C., Ryou, Chongsuk
Format: Online
Language:English
Published: Public Library of Science 2011
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3065467/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3065467/

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