Contributions of KATP and KCa channels to cerebral arteriolar dilation to hypercapnia in neonatal brain

Mechanisms by which Pco2 controls cerebral vascular tone remain uncertain. We hypothesize that potassium channel activation contributes to the neonatal cerebrovascular dilation in response to increases in Paco2. To test this hypothesis, experiments were performed on newborn pigs with surgically impl...

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Bibliographic Details
Main Authors: Nnorom, Chukwuma C., Davis, Corinne, Fedinec, Alexander L., Howell, Khadesia, Jaggar, Jonathan H., Parfenova, Helena, Pourcyrous, Massroor, Leffler, Charles W.
Format: Online
Language:English
Published: Wiley Periodicals, Inc. 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4246596/