Genetic Loci for Retinal Arteriolar Microcirculation

Narrow arterioles in the retina have been shown to predict hypertension as well as other vascular diseases, likely through an increase in the peripheral resistance of the microcirculatory flow. In this study, we performed a genome-wide association study in 18,722 unrelated individuals of European an...

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Main Authors: Sim, Xueling, Jensen, Richard A., Ikram, M. Kamran, Cotch, Mary Frances, Li, Xiaohui, MacGregor, Stuart, Xie, Jing, Smith, Albert Vernon, Boerwinkle, Eric, Mitchell, Paul, Klein, Ronald, Klein, Barbara E. K., Glazer, Nicole L., Lumley, Thomas, McKnight, Barbara, Psaty, Bruce M., de Jong, Paulus T. V. M., Hofman, Albert, Rivadeneira, Fernando, Uitterlinden, Andre G., van Duijn, Cornelia M., Aspelund, Thor, Eiriksdottir, Gudny, Harris, Tamara B., Jonasson, Fridbert, Launer, Lenore J., Attia, John, Baird, Paul N., Harrap, Stephen, Holliday, Elizabeth G., Inouye, Michael, Rochtchina, Elena, Scott, Rodney J., Viswanathan, Ananth, Li, Guo, Smith, Nicholas L., Wiggins, Kerri L., Kuo, Jane Z., Taylor, Kent D., Hewitt, Alex W., Martin, Nicholas G., Montgomery, Grant W., Sun, Cong, Young, Terri L., Mackey, David A., van Zuydam, Natalie R., Doney, Alex S. F., Palmer, Colin N. A., Morris, Andrew D., Rotter, Jerome I., Tai, E. Shyong, Gudnason, Vilmundur, Vingerling, Johannes R., Siscovick, David S., Wang, Jie Jin, Wong, Tien Y.
Format: Online
Language:English
Published: Public Library of Science 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3680438/