Transcription bypass of DNA lesions enhances cell survival but attenuates transcription coupled DNA repair

Transcription-coupled DNA repair (TCR) is a subpathway of nucleotide excision repair (NER) dedicated to rapid removal of DNA lesions in the transcribed strand of actively transcribed genes. The precise nature of the TCR signal and how the repair machinery gains access to lesions imbedded in stalled...

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Bibliographic Details
Main Authors: Li, Wentao, Selvam, Kathiresan, Ko, Tengyu, Li, Shisheng
Format: Online
Language:English
Published: Oxford University Press 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4245964/