UVSSA and USP7, a new couple in transcription-coupled DNA repair

Transcription-coupled nucleotide excision repair (TC-NER) specifically removes transcription-blocking lesions from our genome. Defects in this pathway are associated with two human disorders: Cockayne syndrome (CS) and UV-sensitive syndrome (UVSS). Despite a similar cellular defect in the UV DNA dam...

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Bibliographic Details
Main Authors: Schwertman, Petra, Vermeulen, Wim, Marteijn, Jurgen A
Format: Online
Language:English
Published: Springer Berlin Heidelberg 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3714559/