Administration of an Antioxidant Prevents Lymphoma Development in Transmitochondrial Mice Overproducing Reactive Oxygen Species
Because of the difficulty to exclude possible involvement of nuclear DNA mutations, it has been a controversial issue whether pathogenic mutations in mitochondrial DNA (mtDNA) and the resultant respiration defects are involved in tumor development. To address this issue, our previous study generated...
Main Authors: | , , , , |
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Format: | Online |
Language: | English |
Published: |
Japanese Association for Laboratory Animal Science
2014
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4244294/ |