Administration of an Antioxidant Prevents Lymphoma Development in Transmitochondrial Mice Overproducing Reactive Oxygen Species

Because of the difficulty to exclude possible involvement of nuclear DNA mutations, it has been a controversial issue whether pathogenic mutations in mitochondrial DNA (mtDNA) and the resultant respiration defects are involved in tumor development. To address this issue, our previous study generated...

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Bibliographic Details
Main Authors: Yamanashi, Haruka, Hashizume, Osamu, Yonekawa, Hiromichi, Nakada, Kazuto, Hayashi, Jun-Ichi
Format: Online
Language:English
Published: Japanese Association for Laboratory Animal Science 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4244294/