Selection of Rodent Species Appropriate for mtDNA Transfer to Generate Transmitochondrial Mito-Mice Expressing Mitochondrial Respiration Defects

Selection of Rodent Species Appropriate for mtDNA Transfer to Generate Transmitochondrial Mito-Mice Expressing Mitochondrial Respiration Defects

Previous reports have shown that transmitochondrial mito-mice with nuclear DNA from Mus musculus and mtDNA from M. spretus do not express respiration defects, whereas those with mtDNA from Rattus norvegicus cannot be generated from ES cybrids with mtDNA from R. norvegicus due to inducing significant...

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Bibliographic Details
Main Authors: Enoki, Shunkei, Shimizu, Akinori, Hayashi, Chisato, Imanishi, Hirotake, Hashizume, Osamu, Mekada, Kazuyuki, Suzuki, Hitoshi, Hashimoto, Tetsuo, Nakada, Kazuto, Hayashi, Jun-Ichi
Format: Online
Language:English
Published: Japanese Association for Laboratory Animal Science 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4160931/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4160931/

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