MycN promotes TRPM7 expression and cell migration in neuroblastoma through a process that involves polyamines
•MycN expression correlates with TRPM7 expression in neuroblastoma (NB) tumors.•Expression of the transmembrane protein TRPM7 correlates with lower overall survival in NB tumors.•MycN promotes TRPM7 mRNA and protein expression and increases TRPM7 channel activity.•TRPM7 regulates NB cell migration.•...
| Main Authors: | , |
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| Format: | Online |
| Language: | English |
| Published: |
Elsevier
2014
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4241534/ |