Allosteric control of the exportin CRM1 unraveled by crystal structure analysis

Nucleocytoplasmic trafficking in eukaryotic cells is a highly regulated and coordinated process which involves an increasing variety of soluble nuclear transport receptors. Generally, transport receptors specifically bind their cargo and facilitate its transition through nuclear pore complexes, aque...

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Bibliographic Details
Main Authors: Monecke, Thomas, Dickmanns, Achim, Ficner, Ralf
Format: Online
Language:English
Published: BlackWell Publishing Ltd 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4231977/