Proteome Folding Kinetics Is Limited by Protein Halflife

How heterogeneous are proteome folding timescales and what physical principles, if any, dictate its limits? We answer this by predicting copy number weighted folding speed distribution – using the native topology – for E.coli and Yeast proteome. E.coli and Yeast proteomes yield very similar distribu...

Full description

Bibliographic Details
Main Authors: Zou, Taisong, Williams, Nickolas, Ozkan, S. Banu, Ghosh, Kingshuk
Format: Online
Language:English
Published: Public Library of Science 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4231061/