Highly Anomalous Energetics of Protein Cold Denaturation Linked to Folding-Unfolding Kinetics

Despite several careful experimental analyses, it is not yet clear whether protein cold-denaturation is just a “mirror image” of heat denaturation or whether it shows unique structural and energetic features. Here we report that, for a well-characterized small protein, heat denaturation and cold den...

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Bibliographic Details
Main Authors: Romero-Romero, M. Luisa, Inglés-Prieto, Alvaro, Ibarra-Molero, Beatriz, Sanchez-Ruiz, Jose M.
Format: Online
Language:English
Published: Public Library of Science 2011
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3146537/