CYLD Negatively Regulates Nontypeable Haemophilus influenzae-Induced IL-8 Expression via Phosphatase MKP-1-Dependent Inhibition of ERK

CYLD Negatively Regulates Nontypeable Haemophilus influenzae-Induced IL-8 Expression via Phosphatase MKP-1-Dependent Inhibition of ERK

Nontypeable Haemophilus influenzae (NTHi), a Gram-negative bacterium, is the primary cause of otitis media in children and the exacerbation of chronic obstructive pulmonary disease in adults. A hallmark of both diseases is an overactive inflammatory response, including the upregulation of chemokines...

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Bibliographic Details
Main Authors: Wang, Wenzhuo Y., Komatsu, Kensei, Huang, Yuxian, Wu, Jing, Zhang, Wenhong, Lee, Ji-Yun, Miyata, Masanori, Xu, Haidong, Li, Jian-Dong
Format: Online
Language:English
Published: Public Library of Science 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4229244/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4229244/

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