MACE: model based analysis of ChIP-exo
Understanding the role of a given transcription factor (TF) in regulating gene expression requires precise mapping of its binding sites in the genome. Chromatin immunoprecipitation-exo, an emerging technique using λ exonuclease to digest TF unbound DNA after ChIP, is designed to reveal transcription...
Main Authors: | , , , , , , , , , , , , , , , |
---|---|
Format: | Online |
Language: | English |
Published: |
Oxford University Press
2014
|
Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4227761/ |