Selective targeting of liver cancer with the endothelial marker CD146

Hepatocellular carcinomas are well-vascularized tumors; the endothelial cells in these tumors have a specific phenotype. Our aim was to develop a new approach for tumor-specific drug delivery with monoclonal antibody targeting of endothelial ligands. CD146, a molecule expressed on the endothelial su...

Full description

Bibliographic Details
Main Authors: Thomann, Stefan, Longerich, Thomas, Bazhin, Alexandr V., Mier, Walter, Schemmer, Peter, Ryschich, Eduard
Format: Online
Language:English
Published: Impact Journals LLC 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4226708/