Combining Hypoxia and Bioreactor Hydrodynamics Boosts Induced Pluripotent Stem Cell Differentiation Towards Cardiomyocytes

Combining Hypoxia and Bioreactor Hydrodynamics Boosts Induced Pluripotent Stem Cell Differentiation Towards Cardiomyocytes

Cardiomyocytes (CMs) derived from induced pluripotent stem cells (iPSCs) hold great promise for patient-specific disease modeling, drug screening and cell therapy. However, existing protocols for CM differentiation of iPSCs besides being highly dependent on the application of expensive growth factor...

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Bibliographic Details
Main Authors:	Correia, Cláudia, Serra, Margarida, Espinha, Nuno, Sousa, Marcos, Brito, Catarina, Burkert, Karsten, Zheng, Yunjie, Hescheler, Jürgen, Carrondo, Manuel J. T., Šarić, Tomo, Alves, Paula M.
Format:	Online
Language:	English
Published:	Springer US 2014
Online Access:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4225049/

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