Optimization of matrix assisted desorption/ionization time of flight mass spectrometry (MALDI-TOF-MS) for the characterization of Bacillus and Brevibacillus species

Optimization of matrix assisted desorption/ionization time of flight mass spectrometry (MALDI-TOF-MS) for the characterization of Bacillus and Brevibacillus species

•Optimization of MALDI-TOF-MS for characterizing Bacillus and Brevibacillus species.•Development of a suitable chemometric workflow for processing raw MALDI-TOF-MS data.•Classification of 7 species from bacteria achieved high accuracy (∼90%).•Allowed to dry at room temperature (ca. 22 °C) for 1 h....

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Main Authors: AlMasoud, Najla, Xu, Yun, Nicolaou, Nicoletta, Goodacre, Royston
Format: Online
Language:English
Published: Elsevier 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4223412/
id pubmed-4223412
recordtype oai_dc
spelling pubmed-42234122014-11-09 Optimization of matrix assisted desorption/ionization time of flight mass spectrometry (MALDI-TOF-MS) for the characterization of Bacillus and Brevibacillus species AlMasoud, Najla Xu, Yun Nicolaou, Nicoletta Goodacre, Royston Article •Optimization of MALDI-TOF-MS for characterizing Bacillus and Brevibacillus species.•Development of a suitable chemometric workflow for processing raw MALDI-TOF-MS data.•Classification of 7 species from bacteria achieved high accuracy (∼90%).•Allowed to dry at room temperature (ca. 22 °C) for 1 h. Elsevier 2014-08-20 /pmc/articles/PMC4223412/ /pubmed/25086893 http://dx.doi.org/10.1016/j.aca.2014.06.032 Text en © Elsevier B.V. All rights reserved.
repository_type Open Access Journal
institution_category Foreign Institution
institution US National Center for Biotechnology Information
building NCBI PubMed
collection Online Access
language English
format Online
author AlMasoud, Najla
Xu, Yun
Nicolaou, Nicoletta
Goodacre, Royston
spellingShingle AlMasoud, Najla
Xu, Yun
Nicolaou, Nicoletta
Goodacre, Royston
Optimization of matrix assisted desorption/ionization time of flight mass spectrometry (MALDI-TOF-MS) for the characterization of Bacillus and Brevibacillus species
author_facet AlMasoud, Najla
Xu, Yun
Nicolaou, Nicoletta
Goodacre, Royston
author_sort AlMasoud, Najla
title Optimization of matrix assisted desorption/ionization time of flight mass spectrometry (MALDI-TOF-MS) for the characterization of Bacillus and Brevibacillus species
title_short Optimization of matrix assisted desorption/ionization time of flight mass spectrometry (MALDI-TOF-MS) for the characterization of Bacillus and Brevibacillus species
title_full Optimization of matrix assisted desorption/ionization time of flight mass spectrometry (MALDI-TOF-MS) for the characterization of Bacillus and Brevibacillus species
title_fullStr Optimization of matrix assisted desorption/ionization time of flight mass spectrometry (MALDI-TOF-MS) for the characterization of Bacillus and Brevibacillus species
title_full_unstemmed Optimization of matrix assisted desorption/ionization time of flight mass spectrometry (MALDI-TOF-MS) for the characterization of Bacillus and Brevibacillus species
title_sort optimization of matrix assisted desorption/ionization time of flight mass spectrometry (maldi-tof-ms) for the characterization of bacillus and brevibacillus species
description •Optimization of MALDI-TOF-MS for characterizing Bacillus and Brevibacillus species.•Development of a suitable chemometric workflow for processing raw MALDI-TOF-MS data.•Classification of 7 species from bacteria achieved high accuracy (∼90%).•Allowed to dry at room temperature (ca. 22 °C) for 1 h.
publisher Elsevier
publishDate 2014
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4223412/
_version_ 1613153427022413824

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