Optimization of matrix assisted desorption/ionization time of flight mass spectrometry (MALDI-TOF-MS) for the characterization of Bacillus and Brevibacillus species

•Optimization of MALDI-TOF-MS for characterizing Bacillus and Brevibacillus species.•Development of a suitable chemometric workflow for processing raw MALDI-TOF-MS data.•Classification of 7 species from bacteria achieved high accuracy (∼90%).•Allowed to dry at room temperature (ca. 22 °C) for 1 h....

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Bibliographic Details
Main Authors: AlMasoud, Najla, Xu, Yun, Nicolaou, Nicoletta, Goodacre, Royston
Format: Online
Language:English
Published: Elsevier 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4223412/