High-Throughput Sequencing of Human Immunoglobulin Variable Regions with Subtype Identification

The humoral immune response plays a critical role in controlling infection, and the rapid adaptation to a broad range of pathogens depends on a highly diverse antibody repertoire. The advent of high-throughput sequencing technologies in the past decade has enabled insights into this immense diversit...

Full description

Bibliographic Details
Main Authors: Schanz, Merle, Liechti, Thomas, Zagordi, Osvaldo, Miho, Enkelejda, Reddy, Sai T., Günthard, Huldrych F., Trkola, Alexandra, Huber, Michael
Format: Online
Language:English
Published: Public Library of Science 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4218849/