Collective and Individual Migration following the Epithelial-Mesenchymal Transition

During cancer progression, malignant cells in the tumour invade surrounding tissues. This transformation of adherent cells to a motile phenotype has been associated with the epithelial mesenchymal transition (EMT). Here, we show that EMT-activated cells migrate through micropillar arrays as a collec...

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Bibliographic Details
Main Authors: Wong, Ian Y., Javaid, Sarah, Wong, Elisabeth A., Perk, Sinem, Haber, Daniel A., Toner, Mehmet, Irimia, Daniel
Format: Online
Language:English
Published: 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4209198/