Quercetin-3-glucoside increases low-density lipoprotein receptor (LDLR) expression, attenuates proprotein convertase subtilisin/kexin 9 (PCSK9) secretion, and stimulates LDL uptake by Huh7 human hepatocytes in culture

Quercetin-3-glucoside increases low-density lipoprotein receptor (LDLR) expression, attenuates proprotein convertase subtilisin/kexin 9 (PCSK9) secretion, and stimulates LDL uptake by Huh7 human hepatocytes in culture

•Quercetin-3-glucoside can increase LDLR expression by hepatocytes.•Quercetin-3-glucoside can reduce PCSK9 secretion by hepatocytes.•Quercetin-3-glucoside can down regulate sortilin expression.•Quercetin-3-glucoside can increase LDL uptake by hepatocytes.•Quercetin-3-glucoside is a potential anti-ch...

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Bibliographic Details
Main Authors: Mbikay, Majambu, Sirois, Francine, Simoes, Sonia, Mayne, Janice, Chrétien, Michel
Format: Online
Language:English
Published: Elsevier 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4208090/

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4208090/

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