FunSeq2: a framework for prioritizing noncoding regulatory variants in cancer

Identification of noncoding drivers from thousands of somatic alterations in a typical tumor is a difficult and unsolved problem. We report a computational framework, FunSeq2, to annotate and prioritize these mutations. The framework combines an adjustable data context integrating large-scale genomi...

Full description

Bibliographic Details
Main Authors: Fu, Yao, Liu, Zhu, Lou, Shaoke, Bedford, Jason, Mu, Xinmeng Jasmine, Yip, Kevin Y, Khurana, Ekta, Gerstein, Mark
Format: Online
Language:English
Published: BioMed Central 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4203974/