Comparison of the Effects of Matrix Metalloproteinase Inhibitors on TNF-α Release from Activated Microglia and TNF-α Converting Enzyme Activity

Matrix metalloproteinases (MMPs) are zinc-dependent endopeptidases that regulate cell-matrix composition and are also involved in processing various bioactive molecules such as cell-surface receptors, chemokines, and cytokines. Our group recently reported that MMP-3, -8, and -9 are upregulated durin...

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Bibliographic Details
Main Authors: Lee, Eun-Jung, Moon, Pyong-Gon, Baek, Moon-Chang, Kim, Hee-Sun
Format: Online
Language:English
Published: The Korean Society of Applied Pharmacology 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4201218/