Comparison of the Effects of Matrix Metalloproteinase Inhibitors on TNF-α Release from Activated Microglia and TNF-α Converting Enzyme Activity
Matrix metalloproteinases (MMPs) are zinc-dependent endopeptidases that regulate cell-matrix composition and are also involved in processing various bioactive molecules such as cell-surface receptors, chemokines, and cytokines. Our group recently reported that MMP-3, -8, and -9 are upregulated durin...
Main Authors: | , , , |
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Format: | Online |
Language: | English |
Published: |
The Korean Society of Applied Pharmacology
2014
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4201218/ |