Human Cytomegalovirus Drives Epigenetic Imprinting of the IFNG Locus in NKG2Chi Natural Killer Cells

Memory type 1 T helper (TH1) cells are characterized by the stable expression of interferon (IFN)-γ as well as by the epigenetic imprinting of the IFNG locus. Among innate cells, NK cells play a crucial role in the defense against cytomegalovirus (CMV) and represent the main source of IFN-γ. Recentl...

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Bibliographic Details
Main Authors: Luetke-Eversloh, Merlin, Hammer, Quirin, Durek, Pawel, Nordström, Karl, Gasparoni, Gilles, Pink, Matthias, Hamann, Alf, Walter, Jörn, Chang, Hyun-Dong, Dong, Jun, Romagnani, Chiara
Format: Online
Language:English
Published: Public Library of Science 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4199780/