New prospects on the NKG2D/NKG2DL system for oncology
The activating immunoreceptor NKG2D endows cytotoxic lymphocytes with the capacity to recognize and eliminate infected or malignant cells. The recognition of such harmful cells is enabled by binding of NKG2D to various MHC class I-related glycoproteins, which are upregulated in the course of viral i...
| Main Authors: | , , , |
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| Format: | Online |
| Language: | English |
| Published: |
Landes Bioscience
2013
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3862635/ |