De-SUMOylation of FOXC2 by SENP3 promotes the epithelial-mesenchymal transition in gastric cancer cells

De-SUMOylation of FOXC2 by SENP3 promotes the epithelial-mesenchymal transition in gastric cancer cells

The impact of cellular oxidative stress in promoting the epithelial-mesenchymal transition (EMT) has been noticed. Our previous study shows that SENP3, a redox-sensitive SUMO2/3-specific protease, accumulates in a variety of cancers, but whether SENP3 and SUMOylation involve in the regulation of EMT...

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Bibliographic Details
Main Authors: Ren, Yan-hua, Liu, Ke-jia, Wang, Ming, Yu, Ya-nan, Yang, Kai, Chen, Qin, Yu, Bin, Wang, Wei, Li, Qi-wei, Wang, Jian, Hou, Zhao-yuan, Fang, Jing-yuan, Yeh, Edward T., Yang, Jie, Yi, Jing
Format: Online
Language:English
Published: Impact Journals LLC 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4196186/

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4196186/

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