SENP1 and SENP2 affect spatial and temporal control of sumoylation in mitosis
Proper temporal and spatial regulation of sumoylation during mitosis is critical for mitotic progression. The SUMO isopeptidases SENP1 and SENP2 localize to key mitotic structures, including kinetochores. Overexpression and RNAi studies demonstrate that SENP1 and SENP2 are important modulators of SU...
Main Authors: | , , |
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Format: | Online |
Language: | English |
Published: |
The American Society for Cell Biology
2013
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3826987/ |