SENP1 and SENP2 affect spatial and temporal control of sumoylation in mitosis

Proper temporal and spatial regulation of sumoylation during mitosis is critical for mitotic progression. The SUMO isopeptidases SENP1 and SENP2 localize to key mitotic structures, including kinetochores. Overexpression and RNAi studies demonstrate that SENP1 and SENP2 are important modulators of SU...

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Bibliographic Details
Main Authors: Cubeñas-Potts, Caelin, Goeres, Jacqueline D., Matunis, Michael J.
Format: Online
Language:English
Published: The American Society for Cell Biology 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3826987/