In situ drug-receptor binding kinetics in single cells: a quantitative label-free study of anti-tumor drug resistance
Many drugs are effective in the early stage of treatment, but patients develop drug resistance after a certain period of treatment, causing failure of the therapy. An important example is Herceptin, a popular monoclonal antibody drug for breast cancer by specifically targeting human epidermal growth...
Main Authors: | Wang, Wei, Yin, Linliang, Gonzalez-Malerva, Laura, Wang, Shaopeng, Yu, Xiaobo, Eaton, Seron, Zhang, Shengtao, Chen, Hong-Yuan, LaBaer, Joshua, Tao, Nongjian |
---|---|
Format: | Online |
Language: | English |
Published: |
Nature Publishing Group
2014
|
Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4196117/ |
Similar Items
-
Measurement of Small Molecule Binding Kinetics on
a Protein Microarray by Plasmonic-Based Electrochemical Impedance
Imaging
by: Liang, Wenbin, et al.
Published: (2014) -
Label-Free Imaging of Histamine Mediated G Protein-Coupled
Receptors Activation in Live
Cells
by: Lu, Jin, et al.
Published: (2016) -
Label-free drug discovery
by: Fang, Ye
Published: (2014) -
Kinetics of small molecule interactions with membrane proteins in single cells measured with mechanical amplification
by: Guan, Yan, et al.
Published: (2015) -
Issues and Applications in Label-Free Quantitative Mass Spectrometry
by: Lai, Xianyin, et al.
Published: (2013)