In situ drug-receptor binding kinetics in single cells: a quantitative label-free study of anti-tumor drug resistance

Many drugs are effective in the early stage of treatment, but patients develop drug resistance after a certain period of treatment, causing failure of the therapy. An important example is Herceptin, a popular monoclonal antibody drug for breast cancer by specifically targeting human epidermal growth...

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Bibliographic Details
Main Authors: Wang, Wei, Yin, Linliang, Gonzalez-Malerva, Laura, Wang, Shaopeng, Yu, Xiaobo, Eaton, Seron, Zhang, Shengtao, Chen, Hong-Yuan, LaBaer, Joshua, Tao, Nongjian
Format: Online
Language:English
Published: Nature Publishing Group 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4196117/