Peroxidasin is essential for eye development in the mouse

Mutations in Peroxidasin (PXDN) cause severe inherited eye disorders in humans, such as congenital cataract, corneal opacity and developmental glaucoma. The role of peroxidasin during eye development is poorly understood. Here, we describe the first Pxdn mouse mutant which was induced by ENU (N-ethy...

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Bibliographic Details
Main Authors: Yan, Xiaohe, Sabrautzki, Sibylle, Horsch, Marion, Fuchs, Helmut, Gailus-Durner, Valerie, Beckers, Johannes, HrabÄ› de Angelis, Martin, Graw, Jochen
Format: Online
Language:English
Published: Oxford University Press 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4189897/