Human Adenovirus-Specific γ/δ and CD8+ T Cells Generated by T-Cell Receptor Transfection to Treat Adenovirus Infection after Allogeneic Stem Cell Transplantation

Human Adenovirus-Specific γ/δ and CD8+ T Cells Generated by T-Cell Receptor Transfection to Treat Adenovirus Infection after Allogeneic Stem Cell Transplantation

Human adenovirus infection is life threatening after allogeneic haematopoietic stem cell transplantation (HSCT). Immunotherapy with donor-derived adenovirus-specific T cells is promising; however, 20% of all donors lack adenovirus-specific T cells. To overcome this, we transfected α/β T cells with m...

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Bibliographic Details
Main Authors: Dörrie, Jan, Krug, Christian, Hofmann, Christian, Müller, Ina, Wellner, Verena, Knippertz, Ilka, Schierer, Stephan, Thomas, Simone, Zipperer, Elke, Printz, Dieter, Fritsch, Gerhard, Schuler, Gerold, Schaft, Niels, Geyeregger, Rene
Format: Online
Language:English
Published: Public Library of Science 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4188623/

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