SPDEF Inhibits Prostate Carcinogenesis by Disrupting a Positive Feedback Loop in Regulation of the Foxm1 Oncogene

SPDEF Inhibits Prostate Carcinogenesis by Disrupting a Positive Feedback Loop in Regulation of the Foxm1 Oncogene

SAM-pointed domain-containing ETS transcription factor (SPDEF) is expressed in normal prostate epithelium. While its expression changes during prostate carcinogenesis (PCa), the role of SPDEF in prostate cancer remains controversial due to the lack of genetic mouse models. In present study, we gener...

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Bibliographic Details
Main Authors: Cheng, Xin-Hua, Black, Markaisa, Ustiyan, Vladimir, Le, Tien, Fulford, Logan, Sridharan, Anusha, Medvedovic, Mario, Kalinichenko, Vladimir V., Whitsett, Jeffrey A., Kalin, Tanya V.
Format: Online
Language:English
Published: Public Library of Science 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4177813/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4177813/

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