The resistance mechanisms of proteasome inhibitor bortezomib
The proteasome inhibitor, bortezomib, a boronic dipeptide which reversibly inhibit the chymotrypsin-like activity at the β5-subunit of proteasome (PSMB5), has marked efficacy against multiple myeloma and several non-Hodgkin’s lymphoma subtypes, and has a potential therapeutic role against other mali...
| Main Authors: | , |
|---|---|
| Format: | Online |
| Language: | English |
| Published: |
BioMed Central
2013
|
| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4177604/ |