The Proteasome Inhibitor Bortezomib Sensitizes AML with Myelomonocytic Differentiation to TRAIL Mediated Apoptosis

Acute myeloid leukemia (AML) is an aggressive stem cell malignancy that is difficult to treat. There are limitations to the current treatment regimes especially after disease relapse, and therefore new therapeutic agents are urgently required which can overcome drug resistance whilst avoiding unnece...

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Bibliographic Details
Main Authors: van Dijk, Marianne, Murphy, Eoin, Morrell, Ruth, Knapper, Steven, O'Dwyer, Michael, Samali, Afshin, Szegezdi, Eva
Format: Online
Language:English
Published: Molecular Diversity Preservation International (MDPI) 2011
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3756416/