Divergent kleisin subunits of cohesin specify mechanisms to tether and release meiotic chromosomes

We show that multiple, functionally specialized cohesin complexes mediate the establishment and two-step release of sister chromatid cohesion that underlies the production of haploid gametes. In C. elegans, the kleisin subunits REC-8 and COH-3/4 differ between meiotic cohesins and endow them with di...

Full description

Bibliographic Details
Main Authors: Severson, Aaron F, Meyer, Barbara J
Format: Online
Language:English
Published: eLife Sciences Publications, Ltd 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4174578/