The NF1 gene revisited – from bench to bedside
Neurofibromatosis type 1 (NF1) is a relatively common tumour predisposition syndrome related to germline aberrations of NF1, a tumour suppressor gene. The gene product neurofibromin is a negative regulator of the Ras cellular proliferation pathway, and also exerts tumour suppression via other mechan...
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Bibliographic Details
| Main Authors: |
Yap, Yoon-Sim,
McPherson, John R,
Ong, Choon-Kiat,
Rozen, Steven G,
Teh, Bin-Tean,
Lee, Ann SG,
Callen, David F |
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| Format: | Online
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| Language: | English |
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| Published: |
Impact Journals LLC
2014
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4171599/
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